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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARK4 All Species: 13.64
Human Site: T497 Identified Species: 27.27
UniProt: Q96L34 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L34 NP_113605.2 752 82520 T497 R R K D S T S T P N N L P P S
Chimpanzee Pan troglodytes XP_512745 736 81102 T482 R R K D S T S T P N N L P P S
Rhesus Macaque Macaca mulatta XP_001105523 666 73735 P449 E G G D R G A P G L A L A R V
Dog Lupus familis XP_541564 690 76525 A472 S A H N P N K A E I P E R R K
Cat Felis silvestris
Mouse Mus musculus Q8CIP4 752 82625 T497 R R K D S T S T P N N L P P S
Rat Rattus norvegicus Q8VHF0 797 88733 P493 R K K S P A V P S S N A A S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508081 736 82480 P485 R K K S S T V P S N N T T S G
Chicken Gallus gallus Q9IA88 798 88848 N514 S C L T S S S N D S S V A L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 S701 R L R I Q P S S P P P T H P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S832 K P S M I H Q S P S M P P S Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 N295 V E Q A K K I N E E I V Q E V
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 T416 F L S Q S P P T F Q Q Q S K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 75.8 88.4 N.A. 97.6 60.4 N.A. 64.4 32.4 N.A. 29.3 N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: 100 94.4 77.9 89.3 N.A. 98.9 73.5 N.A. 77.3 50 N.A. 41.2 N.A. N.A. N.A. 46.9 N.A.
P-Site Identity: 100 100 13.3 0 N.A. 100 20 N.A. 40 20 N.A. 33.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 20 6.6 N.A. 100 33.3 N.A. 46.6 46.6 N.A. 46.6 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.5 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 44.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 9 9 9 0 0 9 9 25 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 34 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 9 9 0 0 0 0 0 0 17 9 0 9 0 9 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 9 9 0 0 9 0 0 9 0 0 0 0 0 17 % G
% His: 0 0 9 0 0 9 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 9 9 0 9 0 0 9 9 0 0 0 0 % I
% Lys: 9 17 42 0 9 9 9 0 0 0 0 0 0 9 9 % K
% Leu: 0 17 9 0 0 0 0 0 0 9 0 34 0 9 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 9 0 9 0 17 0 34 42 0 0 0 0 % N
% Pro: 0 9 0 0 17 17 9 25 42 9 17 9 34 34 0 % P
% Gln: 0 0 9 9 9 0 9 0 0 9 9 9 9 0 9 % Q
% Arg: 50 25 9 0 9 0 0 0 0 0 0 0 9 17 0 % R
% Ser: 17 0 17 17 50 9 42 17 17 25 9 0 9 25 50 % S
% Thr: 0 0 0 9 0 34 0 34 0 0 0 17 9 0 0 % T
% Val: 9 0 0 0 0 0 17 0 0 0 0 17 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _